Scientists at Sanford-Burnham Medical Research Institute have discovered a combination of two FDA-approved drugs that appears to stop — and possibly reverse — the destructive changes in the brain caused by Alzheimer’s disease.
By combining two widely used drugs, nitroglycerin and memantine, researchers created a third drug: NitroMemantine. In animal models, the hybrid appears to restore synapses — the connections between neurons — lost in the disease process, according to findings from a 10-year study published this week in the Proceedings of the National Academy of Sciences.
